BDBM50085242 CHEMBL3427653

SMILES: COc1cccc(CCn2cccc(\C=C\C(=O)NO)c2=O)c1

InChI Key: InChIKey=MAKZKVULZPYPKE-BQYQJAHWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50085242 (CHEMBL3427653) Show SMILES COc1cccc(CCn2cccc(\C=C\C(=O)NO)c2=O)c1 Show InChI InChI=1S/C17H18N2O4/c1-23-15-6-2-4-13(12-15)9-11-19-10-3-5-14(17(19)21)7-8-16(20)18-22/h2-8,10,12,22H,9,11H2,1H3,(H,18,20)/b8-7+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading...				J Med Chem 58: 3512-21 (2015) Article DOI: 10.1021/acs.jmedchem.5b00062 BindingDB Entry DOI: 10.7270/Q2GB25R3
					More data for this Ligand-Target Pair