BDBM50085451 (3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide::CHEMBL79705
SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CC[C@H]3CC[C@@](O)(Cc4ccccc4)C(=O)N23)cc1
InChI Key: InChIKey=PVTGBPNXHBYAJX-MZLICYQSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50085451 ((3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-ind...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montr£al Curated by ChEMBL | Assay Description The compound was evaluated for binding affinity against Prothrombin | Bioorg Med Chem Lett 10: 243-7 (2000) BindingDB Entry DOI: 10.7270/Q2K9381W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50085451 ((3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-ind...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Montr£al Curated by ChEMBL | Assay Description Concentration required for 50 percent inhibition of Prothrombin | Bioorg Med Chem Lett 10: 243-7 (2000) BindingDB Entry DOI: 10.7270/Q2K9381W | |||||||||||
More data for this Ligand-Target Pair |