null

SMILES: NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3ccccn3)CC2)C1=O

InChI Key: InChIKey=HJNWBAQDUVUXHQ-UHFFFAOYSA-O

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50085523 (Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...) Show SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3ccccn3)CC2)C1=O Show InChI InChI=1S/C23H30N6O/c24-22(25)18-6-5-8-21(16-18)29-13-4-3-12-28(23(29)30)20-9-14-27(15-10-20)17-19-7-1-2-11-26-19/h1-2,5-8,11,16,20H,3-4,9-10,12-15,17H2,(H3,24,25)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of coagulation factor Xa				Bioorg Med Chem Lett 10: 301-4 (2000) BindingDB Entry DOI: 10.7270/Q2639Q7R
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50085523 (Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...) Show SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3ccccn3)CC2)C1=O Show InChI InChI=1S/C23H30N6O/c24-22(25)18-6-5-8-21(16-18)29-13-4-3-12-28(23(29)30)20-9-14-27(15-10-20)17-19-7-1-2-11-26-19/h1-2,5-8,11,16,20H,3-4,9-10,12-15,17H2,(H3,24,25)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibitory activity against trypsin				Bioorg Med Chem Lett 10: 301-4 (2000) BindingDB Entry DOI: 10.7270/Q2639Q7R
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50085523 (Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...) Show SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3ccccn3)CC2)C1=O Show InChI InChI=1S/C23H30N6O/c24-22(25)18-6-5-8-21(16-18)29-13-4-3-12-28(23(29)30)20-9-14-27(15-10-20)17-19-7-1-2-11-26-19/h1-2,5-8,11,16,20H,3-4,9-10,12-15,17H2,(H3,24,25)/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibitory activity against thrombin				Bioorg Med Chem Lett 10: 301-4 (2000) BindingDB Entry DOI: 10.7270/Q2639Q7R
					More data for this Ligand-Target Pair