BDBM50085607 CHEMBL126365::[1-Oxo-6-((E)-3-piperidin-4-yl-acryloylamino)-1,2,3,4-tetrahydro-naphthalen-2-yl]-acetic acid

SMILES: OC(=O)CC1CCc2cc(NC(=O)\C=C\C3CCNCC3)ccc2C1=O

InChI Key: InChIKey=FNHRZNMQPPDBFU-LZCJLJQNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50085607 (CHEMBL126365 | [1-Oxo-6-((E)-3-piperidin-4-yl-acry...) Show SMILES OC(=O)CC1CCc2cc(NC(=O)\C=C\C3CCNCC3)ccc2C1=O Show InChI InChI=1S/C20H24N2O4/c23-18(6-1-13-7-9-21-10-8-13)22-16-4-5-17-14(11-16)2-3-15(20(17)26)12-19(24)25/h1,4-6,11,13,15,21H,2-3,7-10,12H2,(H,22,23)(H,24,25)/b6-1+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of fibrinogen binding to purified human GPIIb-IIIa in ELISA				Bioorg Med Chem Lett 10: 385-9 (2000) BindingDB Entry DOI: 10.7270/Q2FB5252
					More data for this Ligand-Target Pair