BDBM50085678 4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-imidazole::CHEMBL284213

SMILES: C1CC(c2cnc[nH]2)c2ccsc2C1

InChI Key: InChIKey=BFSPTAYUYXLBEU-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50085678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity towards alpha-2D adrenergic receptor				J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro rat alpha-2D adrenergic receptor binding using p-aminoclonidine				J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description in vitro alpha-2A adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligand				J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity towards Alpha-2A adrenergic receptor				J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity towards Alpha-2B adrenergic receptor				J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (NEONATAL RAT)	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description in vitro alpha-2B adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligand				J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Tested for Binding affinity towards alpha-1 adrenergic receptor				J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity towards alpha-2C adrenergic receptor				J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (RAT)	BDBM50085678 (4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-im...) Show SMILES C1CC(c2cnc[nH]2)c2ccsc2C1 Show InChI InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description in vitro alpha-2C adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligand				J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK
					More data for this Ligand-Target Pair