BDBM50085681 4-Benzo[b]thiophen-4-yl-1H-imidazole::CHEMBL30534
SMILES: c1cc2c(cccc2s1)-c1c[nH]cn1
InChI Key: InChIKey=QRRRICPYXPJYEH-UHFFFAOYSA-N
Data: 7 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2A adrenergic receptor (Rattus norvegicus (rat)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro rat alpha-2D adrenergic receptor binding using p-aminoclonidine | J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Rattus norvegicus (rat)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity towards alpha-2D adrenergic receptor | J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Rattus norvegicus (rat)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 277 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description in vitro alpha-2A adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligand | J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 277 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity towards Alpha-2A adrenergic receptor | J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 343 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Tested for Binding affinity towards alpha-1 adrenergic receptor | J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 663 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity towards Alpha-2B adrenergic receptor | J Med Chem 43: 765-8 (2000) BindingDB Entry DOI: 10.7270/Q2251HDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (NEONATAL RAT) | BDBM50085681 (4-Benzo[b]thiophen-4-yl-1H-imidazole | CHEMBL30534) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 663 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description in vitro alpha-2B adrenergic receptor binding assay from rats ,using RX 821002 as the displaceable ligand | J Med Chem 43: 1423-6 (2001) BindingDB Entry DOI: 10.7270/Q2C828HK | |||||||||||
More data for this Ligand-Target Pair |