null

SMILES: CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(=O)NC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@H]1C=CCN1C(C)=O

InChI Key: InChIKey=MNVKKXLKMFBLDC-JENCGPGLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50085815 (CHEMBL269726 | cyclo(4-10)[Ac-3Pro-DFpa-DTrp-c[Asp...) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(=O)NC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@H]1C=CCN1C(C)=O |c:104| Show InChI InChI=1S/C73H87FN16O13/c1-40(2)31-53-64(95)81-52(15-8-28-78-73(76)77)72(103)90-30-10-17-61(90)71(102)88-59(63(75)94)39-80-62(93)37-58(69(100)83-54(34-43-21-26-49(92)27-22-43)65(96)84-56(67(98)82-53)35-44-18-23-45-11-4-5-12-46(45)32-44)86-68(99)57(36-47-38-79-51-14-7-6-13-50(47)51)85-66(97)55(33-42-19-24-48(74)25-20-42)87-70(101)60-16-9-29-89(60)41(3)91/h4-7,9,11-14,16,18-27,32,38,40,52-61,79,92H,8,10,15,17,28-31,33-37,39H2,1-3H3,(H2,75,94)(H,80,93)(H,81,95)(H,82,98)(H,83,100)(H,84,96)(H,85,97)(H,86,99)(H,87,101)(H,88,102)(H4,76,77,78)/t52-,53+,54+,55-,56+,57-,58+,59+,60-,61+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity of the compound towards Gonadotropin-releasing hormone receptor				J Med Chem 43: 819-28 (2000) BindingDB Entry DOI: 10.7270/Q24X570Z
					More data for this Ligand-Target Pair