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BDBM50085829 CHEMBL355406::Phosphoric acid mono-[4-(2-amino-6-methylamino-purin-9-yl)-2-phosphonooxy-cyclopentyl] ester

SMILES: CNc1nc(N)nc2n(cnc12)[C@@H]1C[C@H](COP(O)(O)=O)[C@@H](C1)OP(O)(O)=O

InChI Key: InChIKey=IHQMVABLPLRMMJ-BWZBUEFSSA-N

Data: 1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085829   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2Y purinoceptor 1


(Meleagris gallopavo)
BDBM50085829
PNG
(CHEMBL355406 | Phosphoric acid mono-[4-(2-amino-6-...)
Show SMILES CNc1nc(N)nc2n(cnc12)[C@@H]1C[C@H](COP(O)(O)=O)[C@@H](C1)OP(O)(O)=O
Show InChI InChI=1S/C12H20N6O8P2/c1-14-10-9-11(17-12(13)16-10)18(5-15-9)7-2-6(4-25-27(19,20)21)8(3-7)26-28(22,23)24/h5-8H,2-4H2,1H3,(H2,19,20,21)(H2,22,23,24)(H3,13,14,16,17)/t6-,7-,8-/m1/s1
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 5.42E+3n/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghosts


Citation and Details
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)
BDBM50085829
PNG
(CHEMBL355406 | Phosphoric acid mono-[4-(2-amino-6-...)
Show SMILES CNc1nc(N)nc2n(cnc12)[C@@H]1C[C@H](COP(O)(O)=O)[C@@H](C1)OP(O)(O)=O
Show InChI InChI=1S/C12H20N6O8P2/c1-14-10-9-11(17-12(13)16-10)18(5-15-9)7-2-6(4-25-27(19,20)21)8(3-7)26-28(22,23)24/h5-8H,2-4H2,1H3,(H2,19,20,21)(H2,22,23,24)(H3,13,14,16,17)/t6-,7-,8-/m1/s1
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/an/a 6.51E+3n/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
In vitro stimulation of 2PY1 purinoceptor mediated phospholipase C (PLC) activity in Turkey Erythrocyte Ghosts


Citation and Details
More data for this
Ligand-Target Pair