BDBM50085906 CHEMBL171577::Decanoic acid 2-hydroxymethyl-4-(3-isopropyl-4-methyl-pentylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester::Decanoic acid 2-hydroxymethyl-4-[3-isopropyl-4-methyl-pent-(Z)-ylidene]-5-oxo-tetrahydro-furan-2-ylmethyl ester
SMILES: CCCCCCCCCC(=O)OCC1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1
InChI Key: InChIKey=PKDPPGRNXLDXPE-KGENOOAVSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50085906 (CHEMBL171577 | Decanoic acid 2-hydroxymethyl-4-(3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute at Frederick Curated by ChEMBL | Assay Description Displacement of [20-3H]-phorbol 12,13-dibutyrate (PDBU) from protein kinase C alpha with phosphatidylserine | J Med Chem 47: 644-55 (2004) Article DOI: 10.1021/jm030454h BindingDB Entry DOI: 10.7270/Q2R49RH2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50085906 (CHEMBL171577 | Decanoic acid 2-hydroxymethyl-4-(3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Binding Affinity against protein kinase C alpha | J Med Chem 43: 921-44 (2000) BindingDB Entry DOI: 10.7270/Q2RN372X | |||||||||||
More data for this Ligand-Target Pair |