BindingDB logo
myBDB logout

BDBM50085909 7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyclopentyl]-heptanoic acid::CHEMBL425681

SMILES: O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1

InChI Key: InChIKey=CCIGYTQGGWYUNA-LELZANKISA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50085909   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
PDB

Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostanoid EP4 receptor expressed in CHO cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for human Prostaglandin D2 receptor expressed in HEK-293 cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 6.91E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostanoid TP receptor expressed in CHO cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostanoid IP receptor


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
NCI pathway
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostaglandin I2 receptor expressed in CHO cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 713n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostanoid EP1 receptor expressed in COS-7 cells.

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
PDB

Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostanoid EP2 receptor expressed in CHO cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 12n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for human Prostanoid FP receptor expressed in COS-7 cells

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))		BDBM50085909
PNG
(7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyc...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1ccccc1
Show InChI InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
PDB

KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Affinity for Prostanoid EP3 receptor expressed in CHO cell line

J Med Chem 43: 945-52 (2000)


BindingDB Entry DOI: 10.7270/Q2MW2GCN
More data for this
Ligand-Target Pair