BDBM50085926 CHEMBL3425587

SMILES: CSC(=S)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=FEGLFSLWHIVPBO-UHFFFAOYSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50085926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 10 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 8 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 12 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 14 by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 6 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 4 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 2 hrs by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 1 hr by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 16 by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50085926 (CHEMBL3425587) Show SMILES CSC(=S)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C8H9NO2S3/c1-13-8(12)9-14(10,11)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 pre-incubated for 18 by stopped-flow CO2 hydration assay				ACS Med Chem Lett 6: 292-5 (2015) Article DOI: 10.1021/ml500470b BindingDB Entry DOI: 10.7270/Q2ZC84KD
					More data for this Ligand-Target Pair