BDBM50085978 CHEMBL7379::[2-(5-Methoxy-2-propyl-1H-indol-3-yl)-ethyl]-dimethyl-amine::[2-(5-Methoxy-2-propyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O4)
SMILES: CCCc1[nH]c2ccc(OC)cc2c1CCN(C)C
InChI Key: InChIKey=BCOTUUNTPYJFKB-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50085978 (CHEMBL7379 | [2-(5-Methoxy-2-propyl-1H-indol-3-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 6 receptor | Bioorg Med Chem Lett 14: 4569-73 (2004) Article DOI: 10.1016/j.bmcl.2004.05.076 BindingDB Entry DOI: 10.7270/Q2CJ8F73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50085978 (CHEMBL7379 | [2-(5-Methoxy-2-propyl-1H-indol-3-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio... | J Med Chem 43: 1011-8 (2000) BindingDB Entry DOI: 10.7270/Q2CF9PBP | |||||||||||
More data for this Ligand-Target Pair |