BDBM50086108 CHEMBL3425702

SMILES: [O-]C(=O)C(F)(F)F.[NH3+]CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12

InChI Key: InChIKey=OETDTSFVQFMRCJ-JXMROGBWSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086108 (CHEMBL3425702) Show SMILES [O-]C(=O)C(F)(F)F.[NH3+]CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12 Show InChI InChI=1S/C22H19ClN4/c23-18-8-5-15(6-9-18)7-10-21-26-20-14-17-4-2-1-3-16(17)13-19(20)22(27-21)25-12-11-24/h1-10,13-14H,11-12,24H2,(H,25,26,27)/p+1/b10-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair