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BDBM50086109 CHEMBL3425701

SMILES: [I-].C[N+](C)(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12

InChI Key: InChIKey=FINNHRGATNRBCD-JLHYYAGUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086109   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division protein FtsZ


(Escherichia coli)		BDBM50086109
PNG
(CHEMBL3425701)
Show SMILES [I-].C[N+](C)(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C25H26ClN4/c1-30(2,3)15-14-27-25-22-16-19-6-4-5-7-20(19)17-23(22)28-24(29-25)13-10-18-8-11-21(26)12-9-18/h4-13,16-17H,14-15H2,1-3H3,(H,27,28,29)/q+1/b13-10+
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Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay

ACS Med Chem Lett 6: 308-12 (2015)


Article DOI: 10.1021/ml500497s
BindingDB Entry DOI: 10.7270/Q2PV6N4C
More data for this
Ligand-Target Pair