BDBM50086245 CHEMBL3425761

SMILES: C(Nc1nc(Cc2ccccc2)cc2CCNCCc12)c1ccccc1

InChI Key: InChIKey=QQMIHTAMSXWKTQ-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50086245 (CHEMBL3425761) Show SMILES C(Nc1nc(Cc2ccccc2)cc2CCNCCc12)c1ccccc1 Show InChI InChI=1S/C23H25N3/c1-3-7-18(8-4-1)15-21-16-20-11-13-24-14-12-22(20)23(26-21)25-17-19-9-5-2-6-10-19/h1-10,16,24H,11-15,17H2,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...				ACS Med Chem Lett 6: 329-33 (2015) Article DOI: 10.1021/ml500507v BindingDB Entry DOI: 10.7270/Q29K4CZW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50086245 (CHEMBL3425761) Show SMILES C(Nc1nc(Cc2ccccc2)cc2CCNCCc12)c1ccccc1 Show InChI InChI=1S/C23H25N3/c1-3-7-18(8-4-1)15-21-16-20-11-13-24-14-12-22(20)23(26-21)25-17-19-9-5-2-6-10-19/h1-10,16,24H,11-15,17H2,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 30 to 40 mins by GTPgammaS recruitment assay				ACS Med Chem Lett 6: 329-33 (2015) Article DOI: 10.1021/ml500507v BindingDB Entry DOI: 10.7270/Q29K4CZW
					More data for this Ligand-Target Pair