BDBM50086352 CHEMBL3426056

SMILES: Cc1cc(cc2c(Nc3ccc(F)c(Cl)c3)ncnc12)-c1cncs1

InChI Key: InChIKey=BIFSNDSAGPUPAP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (Mus musculus)	BDBM50086352 (CHEMBL3426056) Show SMILES Cc1cc(cc2c(Nc3ccc(F)c(Cl)c3)ncnc12)-c1cncs1 Show InChI InChI=1S/C18H12ClFN4S/c1-10-4-11(16-7-21-9-25-16)5-13-17(10)22-8-23-18(13)24-12-2-3-15(20)14(19)6-12/h2-9H,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysis				J Med Chem 58: 3548-71 (2015) Article DOI: 10.1021/jm502009h BindingDB Entry DOI: 10.7270/Q2NV9M00
					More data for this Ligand-Target Pair
Lymphocyte differentiation antigen CD38 (Homo sapiens (Human))	BDBM50086352 (CHEMBL3426056) Show SMILES Cc1cc(cc2c(Nc3ccc(F)c(Cl)c3)ncnc12)-c1cncs1 Show InChI InChI=1S/C18H12ClFN4S/c1-10-4-11(16-7-21-9-25-16)5-13-17(10)22-8-23-18(13)24-12-2-3-15(20)14(19)6-12/h2-9H,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assay				J Med Chem 58: 3548-71 (2015) Article DOI: 10.1021/jm502009h BindingDB Entry DOI: 10.7270/Q2NV9M00
					More data for this Ligand-Target Pair