BDBM50086359 CHEMBL147191::N-Cyclohexylmethyl-2,2-dimethyl-3-methylamino-3-phenyl-propionamide
SMILES: CNC(c1ccccc1)C(C)(C)C(=O)NCC1CCCCC1
InChI Key: InChIKey=PRJJTKSOBSDZRY-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50086359 (CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells | Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50086359 (CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 | Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50086359 (CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells | Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79 | |||||||||||
More data for this Ligand-Target Pair |