BDBM50086851 2-Methoxy-5-methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL356945
SMILES: COc1ccc(SC)cc1C(=O)NC[C@@H]1CCCN1CCc1ccccc1
InChI Key: InChIKey=WFLPEXKCKZHVKQ-SFHVURJKSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50086851 (2-Methoxy-5-methylsulfanyl-N-((S)-1-phenethyl-pyrr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50086851 (2-Methoxy-5-methylsulfanyl-N-((S)-1-phenethyl-pyrr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]ketanserin | Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50086851 (2-Methoxy-5-methylsulfanyl-N-((S)-1-phenethyl-pyrr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity for Dopamine receptor D2 by displacement of [3H]-spiperone | Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T | |||||||||||
More data for this Ligand-Target Pair |