BDBM50087089 (2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](hydroxy)phosphoryl}-2-benzylpropanamido]-3-phenylpropanoic acid::1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl-propyl]-hydroxy-phosphinoyl}-2-phenyl-ethyl-ammonium
SMILES: [NH3+][C@H](Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
InChI Key: InChIKey=XNPYGVCNHOXQRJ-DSITVLBTSA-O
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50087089 ((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50087089 ((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50087089 ((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50087089 ((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50087089 ((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description inhibitory activity on angiotensin I converting enzyme (ACE) using cbz-Phe-His-Leu as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair |