BDBM50087096 1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl-propyl]-hydroxy-phosphinoyl}-3-methyl-butyl-ammonium
SMILES: CC(C)CC([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
InChI Key: InChIKey=TXXKMCPWNCYHRN-LKXRKSRJSA-O
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50087096 (1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50087096 (1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate. | J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J | |||||||||||
More data for this Ligand-Target Pair |