BDBM50087125 CHEMBL3426640

SMILES: COCCOC(=O)c1ccc(F)c(c1)C(=O)Nc1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F

InChI Key: InChIKey=WCHCYBGLVMXBGU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087125 (CHEMBL3426640) Show SMILES COCCOC(=O)c1ccc(F)c(c1)C(=O)Nc1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F Show InChI InChI=1S/C30H26F2N4O5/c1-40-11-12-41-30(39)20-7-8-25(31)24(15-20)29(38)35-22-4-2-3-18(13-22)23-14-19(5-6-21(23)16-33)28(37)36-27-9-10-34-17-26(27)32/h2-10,13-15,17H,11-12,16,33H2,1H3,(H,35,38)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087125 (CHEMBL3426640) Show SMILES COCCOC(=O)c1ccc(F)c(c1)C(=O)Nc1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F Show InChI InChI=1S/C30H26F2N4O5/c1-40-11-12-41-30(39)20-7-8-25(31)24(15-20)29(38)35-22-4-2-3-18(13-22)23-14-19(5-6-21(23)16-33)28(37)36-27-9-10-34-17-26(27)32/h2-10,13-15,17H,11-12,16,33H2,1H3,(H,35,38)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
					More data for this Ligand-Target Pair