BDBM50087279 CHEMBL3426643

SMILES: NCc1ccc(cc1-c1cccc(c1)C(=O)Nc1cc(ccc1F)C(O)=O)C(=O)Nc1ccncc1F

InChI Key: InChIKey=XGQPKOMRSPKVIF-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087279 (CHEMBL3426643) Show SMILES NCc1ccc(cc1-c1cccc(c1)C(=O)Nc1cc(ccc1F)C(O)=O)C(=O)Nc1ccncc1F Show InChI InChI=1S/C27H20F2N4O4/c28-21-7-6-18(27(36)37)12-24(21)33-25(34)16-3-1-2-15(10-16)20-11-17(4-5-19(20)13-30)26(35)32-23-8-9-31-14-22(23)29/h1-12,14H,13,30H2,(H,33,34)(H,36,37)(H,31,32,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
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