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BDBM50087536 3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic acid (2'-methanesulfonyl-biphenyl-4-yl)-amide::CHEMBL159816

SMILES: CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2conc2-c2cccc(c2)C(N)=N)cc1

InChI Key: InChIKey=GBHRGFDZVUNZDA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50087536
PNG
(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2conc2-c2cccc(c2)C(N)=N)cc1
Show InChI InChI=1S/C24H20N4O4S/c1-33(30,31)21-8-3-2-7-19(21)15-9-11-18(12-10-15)27-24(29)20-14-32-28-22(20)16-5-4-6-17(13-16)23(25)26/h2-14H,1H3,(H3,25,26)(H,27,29)
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0.100n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Inhibition of human Coagulation factor X


Bioorg Med Chem Lett 10: 685-9 (2000)


BindingDB Entry DOI: 10.7270/Q21V5D63
More data for this
Ligand-Target Pair
Trypsin


(Bos taurus (bovine))
BDBM50087536
PNG
(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2conc2-c2cccc(c2)C(N)=N)cc1
Show InChI InChI=1S/C24H20N4O4S/c1-33(30,31)21-8-3-2-7-19(21)15-9-11-18(12-10-15)27-24(29)20-14-32-28-22(20)16-5-4-6-17(13-16)23(25)26/h2-14H,1H3,(H3,25,26)(H,27,29)
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KEGG

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PubMed
25n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Inhibitory activity against trypsin


Bioorg Med Chem Lett 10: 685-9 (2000)


BindingDB Entry DOI: 10.7270/Q21V5D63
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM50087536
PNG
(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2conc2-c2cccc(c2)C(N)=N)cc1
Show InChI InChI=1S/C24H20N4O4S/c1-33(30,31)21-8-3-2-7-19(21)15-9-11-18(12-10-15)27-24(29)20-14-32-28-22(20)16-5-4-6-17(13-16)23(25)26/h2-14H,1H3,(H3,25,26)(H,27,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
540n/an/an/an/an/an/an/an/a



The DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin


Bioorg Med Chem Lett 10: 685-9 (2000)


BindingDB Entry DOI: 10.7270/Q21V5D63
More data for this
Ligand-Target Pair