BDBM50087539 (4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-dihydro-isoxazole-4-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL436235

SMILES: C[C@H]1ON=C([C@@H]1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N

InChI Key: InChIKey=MADZMQMBPVBDFK-SPLOXXLWSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50087539 ((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...) Show SMILES C[C@H]1ON=C([C@@H]1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N |c:3| Show InChI InChI=1S/C24H23N5O4S/c1-14-21(22(29-33-14)16-5-4-6-17(13-16)23(25)26)24(30)28-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,31)32/h2-14,21H,1H3,(H3,25,26)(H,28,30)(H2,27,31,32)/t14-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of human Coagulation factor X				Bioorg Med Chem Lett 10: 685-9 (2000) BindingDB Entry DOI: 10.7270/Q21V5D63
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50087539 ((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...) Show SMILES C[C@H]1ON=C([C@@H]1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N |c:3| Show InChI InChI=1S/C24H23N5O4S/c1-14-21(22(29-33-14)16-5-4-6-17(13-16)23(25)26)24(30)28-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,31)32/h2-14,21H,1H3,(H3,25,26)(H,28,30)(H2,27,31,32)/t14-,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibitory activity against trypsin				Bioorg Med Chem Lett 10: 685-9 (2000) BindingDB Entry DOI: 10.7270/Q21V5D63
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50087539 ((4S,5R)-3-(3-Carbamimidoyl-phenyl)-5-methyl-4,5-di...) Show SMILES C[C@H]1ON=C([C@@H]1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N |c:3| Show InChI InChI=1S/C24H23N5O4S/c1-14-21(22(29-33-14)16-5-4-6-17(13-16)23(25)26)24(30)28-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,31)32/h2-14,21H,1H3,(H3,25,26)(H,28,30)(H2,27,31,32)/t14-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibitory activity against thrombin				Bioorg Med Chem Lett 10: 685-9 (2000) BindingDB Entry DOI: 10.7270/Q21V5D63
					More data for this Ligand-Target Pair