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BDBM50087669 Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-methyl-piperazine-1-carbonyl)-5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl]-phenyl}-amide; compound with 3-carboxy-3-hydroxy-pentanedioic acid::CHEMBL164387

SMILES: CN1CCN(CC1)C(=O)c1ccc2CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3Cl)c3ccccc3Cn12

InChI Key: InChIKey=QZDNKVRFWDKMFY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087669   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vasopressin V2 receptor


(Homo sapiens (Human))		BDBM50087669
PNG
(Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-methy...)
Show SMILES CN1CCN(CC1)C(=O)c1ccc2CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3Cl)c3ccccc3Cn12
Show InChI InChI=1S/C38H34ClN5O3/c1-41-19-21-42(22-20-41)38(47)35-18-16-29-25-44(34-14-8-5-11-27(34)24-43(29)35)37(46)32-17-15-28(23-33(32)39)40-36(45)31-13-7-6-12-30(31)26-9-3-2-4-10-26/h2-18,23H,19-22,24-25H2,1H3,(H,40,45)
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 12n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes

Bioorg Med Chem Lett 10: 783-6 (2000)


BindingDB Entry DOI: 10.7270/Q24M93RK
More data for this
Ligand-Target Pair