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BDBM50087768 3-[3-(4-Dimethylamino-phenyl)-3-oxo-propenyl]-benzamide::CHEMBL43771

SMILES: CN(C)c1ccc(cc1)C(=O)\C=C\c1cccc(c1)C(N)=O

InChI Key: InChIKey=LBGYCHWWYVAIGE-IZZDOVSWSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087768   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human rhinovirus A protease


(Human rhinovirus B)
BDBM50087768
PNG
(3-[3-(4-Dimethylamino-phenyl)-3-oxo-propenyl]-benz...)
Show SMILES CN(C)c1ccc(cc1)C(=O)\C=C\c1cccc(c1)C(N)=O
Show InChI InChI=1S/C18H18N2O2/c1-20(2)16-9-7-14(8-10-16)17(21)11-6-13-4-3-5-15(12-13)18(19)22/h3-12H,1-2H3,(H2,19,22)/b11-6+
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
9.00E+3n/an/an/an/an/an/an/an/a



Agouron Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.


J Med Chem 43: 1670-83 (2000)


BindingDB Entry DOI: 10.7270/Q2GX49ST
More data for this
Ligand-Target Pair
Human rhinovirus A protease


(Human rhinovirus B)
BDBM50087768
PNG
(3-[3-(4-Dimethylamino-phenyl)-3-oxo-propenyl]-benz...)
Show SMILES CN(C)c1ccc(cc1)C(=O)\C=C\c1cccc(c1)C(N)=O
Show InChI InChI=1S/C18H18N2O2/c1-20(2)16-9-7-14(8-10-16)17(21)11-6-13-4-3-5-15(12-13)18(19)22/h3-12H,1-2H3,(H2,19,22)/b11-6+
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a>1.50E+4n/an/an/an/a



Agouron Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Antiviral activity using H1HeLa cells (ATCC) infected with HRV-14


J Med Chem 43: 1670-83 (2000)


BindingDB Entry DOI: 10.7270/Q2GX49ST
More data for this
Ligand-Target Pair