BDBM50088109 CHEMBL55521::N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-(2-methyl-benzene)-sulfonyl)ureido-benzenesulfonyl)-amino]-acetamide

SMILES: Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=MOHDKNTXJIGORP-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50088109 (CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...) Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O9S2/c1-16-4-2-3-5-21(16)38(34,35)26-23(30)24-18-8-12-20(13-9-18)39(36,37)27(15-22(29)25-31)14-17-6-10-19(11-7-17)28(32)33/h2-13,31H,14-15H2,1H3,(H,25,29)(H2,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix metalloprotease-9				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50088109 (CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...) Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O9S2/c1-16-4-2-3-5-21(16)38(34,35)26-23(30)24-18-8-12-20(13-9-18)39(36,37)27(15-22(29)25-31)14-17-6-10-19(11-7-17)28(32)33/h2-13,31H,14-15H2,1H3,(H,25,29)(H2,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease-8				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50088109 (CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...) Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O9S2/c1-16-4-2-3-5-21(16)38(34,35)26-23(30)24-18-8-12-20(13-9-18)39(36,37)27(15-22(29)25-31)14-17-6-10-19(11-7-17)28(32)33/h2-13,31H,14-15H2,1H3,(H,25,29)(H2,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50088109 (CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...) Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O9S2/c1-16-4-2-3-5-21(16)38(34,35)26-23(30)24-18-8-12-20(13-9-18)39(36,37)27(15-22(29)25-31)14-17-6-10-19(11-7-17)28(32)33/h2-13,31H,14-15H2,1H3,(H,25,29)(H2,24,26,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Clostridium histolyticum collagenase (ChC)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50088109 (CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...) Show SMILES Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O9S2/c1-16-4-2-3-5-21(16)38(34,35)26-23(30)24-18-8-12-20(13-9-18)39(36,37)27(15-22(29)25-31)14-17-6-10-19(11-7-17)28(32)33/h2-13,31H,14-15H2,1H3,(H,25,29)(H2,24,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
					More data for this Ligand-Target Pair