BindingDB PrimarySearch

BDBM50088128 2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nonafluorobutan-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL55110::N-Hydroxy-2-[(4-nitro-benzyl)-(nonafluorobutane-1-sulfonyl)-amino]-acetamide

SMILES: ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI Key: InChIKey=UGMRVUAZVAXFHK-UHFFFAOYSA-N

Data: 7 KI 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50088128
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
Università degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
Pomona College Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
Pomona College Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix metalloprotease-9				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
Università degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease-8				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
Università degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Clostridium histolyticum collagenase (ChC)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
Università degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)				J Med Chem 43: 1858-65 (2000) BindingDB Entry DOI: 10.7270/Q2ZW1K4G
Università degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50088128 (2-(N-(4-nitrobenzyl)-4,4,12,12,15,15,18,18,18-nona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
Pomona College Curated by ChEMBL					More data for this Ligand-Target Pair