BDBM50088221 CHEMBL293118::E-2-Amino-4-[3-(3,4-dichloro-phenyl)-allyl]-pentanedioic acid

SMILES: N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)c(Cl)c1)C(O)=O)C(O)=O

InChI Key: InChIKey=LKTLFIMGQSMIDT-BNKUZUHGSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM50088221 (CHEMBL293118 | E-2-Amino-4-[3-(3,4-dichloro-phenyl...) Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)c(Cl)c1)C(O)=O)C(O)=O Show InChI InChI=1S/C14H15Cl2NO4/c15-10-5-4-8(6-11(10)16)2-1-3-9(13(18)19)7-12(17)14(20)21/h1-2,4-6,9,12H,3,7,17H2,(H,18,19)(H,20,21)/b2-1+/t9-,12+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, S.A. Curated by ChEMBL					Assay Description Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand				J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50088221 (CHEMBL293118 | E-2-Amino-4-[3-(3,4-dichloro-phenyl...) Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)c(Cl)c1)C(O)=O)C(O)=O Show InChI InChI=1S/C14H15Cl2NO4/c15-10-5-4-8(6-11(10)16)2-1-3-9(13(18)19)7-12(17)14(20)21/h1-2,4-6,9,12H,3,7,17H2,(H,18,19)(H,20,21)/b2-1+/t9-,12+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.99E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, S.A. Curated by ChEMBL					Assay Description Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligand				J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB
					More data for this Ligand-Target Pair