BDBM50088249 5,5'-diiodo-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3-dihydro-1H-indene]-6,6'-diol::CHEMBL62901

SMILES: CC1(C)CC2(CC(C)(C)c3cc(I)c(O)cc23)c2cc(O)c(I)cc12

InChI Key: InChIKey=WAPOQQAKVDHZNM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50088249 (5,5'-diiodo-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3...) Show SMILES CC1(C)CC2(CC(C)(C)c3cc(I)c(O)cc23)c2cc(O)c(I)cc12 Show InChI InChI=1S/C21H22I2O2/c1-19(2)9-21(13-7-17(24)15(22)5-11(13)19)10-20(3,4)12-6-16(23)18(25)8-14(12)21/h5-8,24-25H,9-10H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of strand -transfer (ST) activity in the presence of Mn2+				J Med Chem 43: 2031-9 (2000) BindingDB Entry DOI: 10.7270/Q2B56J0B
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50088249 (5,5'-diiodo-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3...) Show SMILES CC1(C)CC2(CC(C)(C)c3cc(I)c(O)cc23)c2cc(O)c(I)cc12 Show InChI InChI=1S/C21H22I2O2/c1-19(2)9-21(13-7-17(24)15(22)5-11(13)19)10-20(3,4)12-6-16(23)18(25)8-14(12)21/h5-8,24-25H,9-10H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro				J Med Chem 43: 2031-9 (2000) BindingDB Entry DOI: 10.7270/Q2B56J0B
					More data for this Ligand-Target Pair