null

SMILES: NC(=O)C1CCCc2c1[nH]nc2-c1nc2ccccc2s1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50088294 (CHEMBL3427761) Show SMILES NC(=O)C1CCCc2c1[nH]nc2-c1nc2ccccc2s1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 2514-8 (2015) Article DOI: 10.1016/j.bmcl.2015.04.068 BindingDB Entry DOI: 10.7270/Q2X63PN0
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50088294 (CHEMBL3427761) Show SMILES NC(=O)C1CCCc2c1[nH]nc2-c1nc2ccccc2s1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 2514-8 (2015) Article DOI: 10.1016/j.bmcl.2015.04.068 BindingDB Entry DOI: 10.7270/Q2X63PN0
					More data for this Ligand-Target Pair