BDBM50088305 1-Methyl-1-{4-[(6-p-tolyl-2H-chromene-3-carbonyl)-amino]-benzyl}-piperidinium; iodide::CHEMBL64591

SMILES: Cc1ccc(cc1)-c1ccc2OCC(=Cc2c1)C(=O)Nc1ccc(C[N+]2(C)CCCCC2)cc1

InChI Key: InChIKey=FWIATNJEFIMESS-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50088305 (1-Methyl-1-{4-[(6-p-tolyl-2H-chromene-3-carbonyl)-...) Show SMILES Cc1ccc(cc1)-c1ccc2OCC(=Cc2c1)C(=O)Nc1ccc(C[N+]2(C)CCCCC2)cc1 |c:14| Show InChI InChI=1S/C30H32N2O2/c1-22-6-10-24(11-7-22)25-12-15-29-26(18-25)19-27(21-34-29)30(33)31-28-13-8-23(9-14-28)20-32(2)16-4-3-5-17-32/h6-15,18-19H,3-5,16-17,20-21H2,1-2H3/p+1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES				J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75
					More data for this Ligand-Target Pair