BDBM50088310 4-Methyl-4-{4-[(7-phenyl-3,4-dihydro-naphthalene-2-carbonyl)-amino]-benzyl}-morpholin-4-ium; iodide::CHEMBL65649

SMILES: C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCOCC1

InChI Key: InChIKey=BFQCGODPILXRAA-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50088310 (4-Methyl-4-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) Show SMILES C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCOCC1 |t:10| Show InChI InChI=1S/C29H30N2O2/c1-31(15-17-33-18-16-31)21-22-7-13-28(14-8-22)30-29(32)26-12-10-24-9-11-25(19-27(24)20-26)23-5-3-2-4-6-23/h2-9,11,13-14,19-20H,10,12,15-18,21H2,1H3/p+1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES				J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75
					More data for this Ligand-Target Pair