BDBM50088323 1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2-carbonyl)-amino]-benzyl}-azepanium; iodide::CHEMBL293882

SMILES: C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCCCCC1

InChI Key: InChIKey=LASDXRKNUJXDEG-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50088323 (1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) Show SMILES C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCCCCC1 |t:10| Show InChI InChI=1S/C31H34N2O/c1-33(19-7-2-3-8-20-33)23-24-11-17-30(18-12-24)32-31(34)28-16-14-26-13-15-27(21-29(26)22-28)25-9-5-4-6-10-25/h4-6,9-13,15,17-18,21-22H,2-3,7-8,14,16,19-20,23H2,1H3/p+1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES				J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75
					More data for this Ligand-Target Pair