BDBM50088324 1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2-carbonyl)-amino]-benzyl}-pyrrolidinium; iodide::CHEMBL65681

SMILES: C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCCC1

InChI Key: InChIKey=FZMBIRYAUDRMOH-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50088324 (1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) Show SMILES C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(ccc4CC3)-c3ccccc3)cc2)CCCC1 |t:10| Show InChI InChI=1S/C29H30N2O/c1-31(17-5-6-18-31)21-22-9-15-28(16-10-22)30-29(32)26-14-12-24-11-13-25(19-27(24)20-26)23-7-3-2-4-8-23/h2-4,7-11,13,15-16,19-20H,5-6,12,14,17-18,21H2,1H3/p+1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES				J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75
					More data for this Ligand-Target Pair