BDBM50088496 CHEMBL3526621

SMILES: C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(CO)cc4c3F)c2c1C

InChI Key: InChIKey=NRYXTTFKQXSWLA-SNVBAGLBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50088496 (CHEMBL3526621) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(CO)cc4c3F)c2c1C |r| Show InChI InChI=1S/C19H19FN4O4/c1-10(26)8-27-16-6-24-18(11(16)2)19(21-9-22-24)28-15-4-3-14-13(17(15)20)5-12(7-25)23-14/h3-6,9-10,23,25-26H,7-8H2,1-2H3/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant FGFR-1				Drug Metab Dispos 39: 891-903 (2011) Article DOI: 10.1124/dmd.110.037341 BindingDB Entry DOI: 10.7270/Q2F191FN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50088496 (CHEMBL3526621) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(CO)cc4c3F)c2c1C |r| Show InChI InChI=1S/C19H19FN4O4/c1-10(26)8-27-16-6-24-18(11(16)2)19(21-9-22-24)28-15-4-3-14-13(17(15)20)5-12(7-25)23-14/h3-6,9-10,23,25-26H,7-8H2,1-2H3/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2				Drug Metab Dispos 39: 891-903 (2011) Article DOI: 10.1124/dmd.110.037341 BindingDB Entry DOI: 10.7270/Q2F191FN
					More data for this Ligand-Target Pair