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BDBM50088525 CHEMBL3526173

SMILES: [H][C@]1(C[C@H]2O[C@]2(C)[C@@]2([H])[C@H](OC)[C@@H](CC[C@]22CO2)OC(=O)N[C@H](C(C)C)C(N)=O)OC1(C)C

InChI Key: InChIKey=UORZAQJPDFQMKM-WCAOZRLVNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088525   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Microtubule-associated protein 2


(Homo sapiens (Human))
BDBM50088525
PNG
(CHEMBL3526173)
Show SMILES [H][C@]1(C[C@H]2O[C@]2(C)[C@@]2([H])[C@H](OC)[C@@H](CC[C@]22CO2)OC(=O)N[C@H](C(C)C)C(N)=O)OC1(C)C |r|
Show InChI InChI=1/C22H36N2O7/c1-11(2)15(18(23)25)24-19(26)29-12-7-8-22(10-28-22)17(16(12)27-6)21(5)14(31-21)9-13-20(3,4)30-13/h11-17H,7-10H2,1-6H3,(H2,23,25)(H,24,26)/t12-,13-,14-,15-,16-,17-,21+,22+/s2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.30n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assay


Drug Metab Dispos 41: 814-26 (2013)


Article DOI: 10.1124/dmd.112.048355
BindingDB Entry DOI: 10.7270/Q2NC62XH
More data for this
Ligand-Target Pair