BDBM50088572 CHEMBL3577209
SMILES: COc1cccc(OC)c1C(=O)c1c(O)cc(C)c(OC)c1CC(=O)c1c(OC)c(C)cc(O)c1C(=O)c1c(OC)cccc1OC
InChI Key: InChIKey=DAFHEWKMPBBGIW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated potassium channel subunit Kv2.1 (Kv2.1) (Homo sapiens (Human)) | BDBM50088572 (CHEMBL3577209) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp technique | J Nat Prod 78: 363-7 (2015) Article DOI: 10.1021/np5007586 BindingDB Entry DOI: 10.7270/Q20P11R5 | |||||||||||
More data for this Ligand-Target Pair |