BDBM50088633 3-(3-Methoxy-phenyl)-5-((R)-pyrrolidin-3-yloxy)-pyridine::CHEMBL10360

SMILES: COc1cccc(c1)-c1cncc(O[C@@H]2CCNC2)c1

InChI Key: InChIKey=RJJJDSXETUUDEB-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088633 (3-(3-Methoxy-phenyl)-5-((R)-pyrrolidin-3-yloxy)-py...) Show SMILES COc1cccc(c1)-c1cncc(O[C@@H]2CCNC2)c1 Show InChI InChI=1S/C16H18N2O2/c1-19-14-4-2-3-12(7-14)13-8-16(11-18-9-13)20-15-5-6-17-10-15/h2-4,7-9,11,15,17H,5-6,10H2,1H3/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair