BDBM50088637 3-Ethynyl-5-((R)-pyrrolidin-3-yloxy)-pyridine::CHEMBL268047

SMILES: C#Cc1cncc(O[C@@H]2CCNC2)c1

InChI Key: InChIKey=GPTBZHNSJACGDU-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088637 (3-Ethynyl-5-((R)-pyrrolidin-3-yloxy)-pyridine | CH...) Show SMILES C#Cc1cncc(O[C@@H]2CCNC2)c1 Show InChI InChI=1S/C11H12N2O/c1-2-9-5-11(8-13-6-9)14-10-3-4-12-7-10/h1,5-6,8,10,12H,3-4,7H2/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair