BDBM50088649 3-(3-Chloro-phenyl)-5-((R)-pyrrolidin-3-yloxy)-pyridine::CHEMBL10173

SMILES: Clc1cccc(c1)-c1cncc(O[C@@H]2CCNC2)c1

InChI Key: InChIKey=WYVKGTMVRMKRMJ-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088649 (3-(3-Chloro-phenyl)-5-((R)-pyrrolidin-3-yloxy)-pyr...) Show SMILES Clc1cccc(c1)-c1cncc(O[C@@H]2CCNC2)c1 Show InChI InChI=1S/C15H15ClN2O/c16-13-3-1-2-11(6-13)12-7-15(10-18-8-12)19-14-4-5-17-9-14/h1-3,6-8,10,14,17H,4-5,9H2/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair