BDBM50088650 2-Chloro-3-ethynyl-5-((R)-pyrrolidin-3-yloxy)-pyridine::CHEMBL269451

SMILES: Clc1ncc(O[C@@H]2CCNC2)cc1C#C

InChI Key: InChIKey=YTDGVDAXBVVHBU-SECBINFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088650 (2-Chloro-3-ethynyl-5-((R)-pyrrolidin-3-yloxy)-pyri...) Show SMILES Clc1ncc(O[C@@H]2CCNC2)cc1C#C Show InChI InChI=1S/C11H11ClN2O/c1-2-8-5-10(7-14-11(8)12)15-9-3-4-13-6-9/h1,5,7,9,13H,3-4,6H2/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair