BDBM50088722 CHEMBL12765::N,N-Diethyl-4-[phenyl-((1R,3R,5S)-8-propyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amino]-benzamide

SMILES: CCCN1[C@H]2CC[C@@H]1C[C@@H](C2)N(c1ccccc1)c1ccc(cc1)C(=O)N(CC)CC

InChI Key: InChIKey=MPRXVSJYTYGFJP-GPOLMCQNSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50088722 (CHEMBL12765 | N,N-Diethyl-4-[phenyl-((1R,3R,5S)-8-...) Show SMILES CCCN1[C@H]2CC[C@@H]1C[C@@H](C2)N(c1ccccc1)c1ccc(cc1)C(=O)N(CC)CC |THB:2:3:9.8.10:5.6| Show InChI InChI=1S/C27H37N3O/c1-4-18-29-24-16-17-25(29)20-26(19-24)30(22-10-8-7-9-11-22)23-14-12-21(13-15-23)27(31)28(5-2)6-3/h7-15,24-26H,4-6,16-20H2,1-3H3/t24-,25+,26+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50088722 (CHEMBL12765 | N,N-Diethyl-4-[phenyl-((1R,3R,5S)-8-...) Show SMILES CCCN1[C@H]2CC[C@@H]1C[C@@H](C2)N(c1ccccc1)c1ccc(cc1)C(=O)N(CC)CC |THB:2:3:9.8.10:5.6| Show InChI InChI=1S/C27H37N3O/c1-4-18-29-24-16-17-25(29)20-26(19-24)30(22-10-8-7-9-11-22)23-14-12-21(13-15-23)27(31)28(5-2)6-3/h7-15,24-26H,4-6,16-20H2,1-3H3/t24-,25+,26+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair