BDBM50088725 4-({(1R,3R,5S)-8-[2-(3,4-Dimethoxy-phenyl)-ethyl]-8-aza-bicyclo[3.2.1]oct-3-yl}-phenyl-amino)-N,N-diethyl-benzamide::CHEMBL13371

SMILES: CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccc(OC)c(OC)c1)c1ccccc1

InChI Key: InChIKey=GUCKXKSRGHSRQI-YHTXFFTCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50088725 (4-({(1R,3R,5S)-8-[2-(3,4-Dimethoxy-phenyl)-ethyl]-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccc(OC)c(OC)c1)c1ccccc1 |THB:22:21:14.20.15:18.17| Show InChI InChI=1S/C34H43N3O3/c1-5-35(6-2)34(38)26-13-15-28(16-14-26)37(27-10-8-7-9-11-27)31-23-29-17-18-30(24-31)36(29)21-20-25-12-19-32(39-3)33(22-25)40-4/h7-16,19,22,29-31H,5-6,17-18,20-21,23-24H2,1-4H3/t29-,30+,31+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50088725 (4-({(1R,3R,5S)-8-[2-(3,4-Dimethoxy-phenyl)-ethyl]-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccc(OC)c(OC)c1)c1ccccc1 |THB:22:21:14.20.15:18.17| Show InChI InChI=1S/C34H43N3O3/c1-5-35(6-2)34(38)26-13-15-28(16-14-26)37(27-10-8-7-9-11-27)31-23-29-17-18-30(24-31)36(29)21-20-25-12-19-32(39-3)33(22-25)40-4/h7-16,19,22,29-31H,5-6,17-18,20-21,23-24H2,1-4H3/t29-,30+,31+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair