BDBM50088740 CHEMBL276243::N-Ethyl-4-[((1R,3S,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-N-(4-methyl-benzyl)-benzamide

SMILES: CCN(Cc1ccc(C)cc1)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2C)c1ccccc1

InChI Key: InChIKey=HFYSESCJQBLKCU-RLPLKTQASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50088740 (CHEMBL276243 | N-Ethyl-4-[((1R,3S,5S)-8-methyl-8-a...) Show SMILES CCN(Cc1ccc(C)cc1)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2C)c1ccccc1 |THB:28:27:20.26.21:23.24| Show InChI InChI=1S/C31H37N3O/c1-4-33(22-24-12-10-23(2)11-13-24)31(35)25-14-16-27(17-15-25)34(26-8-6-5-7-9-26)30-20-28-18-19-29(21-30)32(28)3/h5-17,28-30H,4,18-22H2,1-3H3/t28-,29+,30-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50088740 (CHEMBL276243 | N-Ethyl-4-[((1R,3S,5S)-8-methyl-8-a...) Show SMILES CCN(Cc1ccc(C)cc1)C(=O)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2C)c1ccccc1 |THB:28:27:20.26.21:23.24| Show InChI InChI=1S/C31H37N3O/c1-4-33(22-24-12-10-23(2)11-13-24)31(35)25-14-16-27(17-15-25)34(26-8-6-5-7-9-26)30-20-28-18-19-29(21-30)32(28)3/h5-17,28-30H,4,18-22H2,1-3H3/t28-,29+,30-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes				Bioorg Med Chem Lett 10: 1109-11 (2000) BindingDB Entry DOI: 10.7270/Q2X0668B
					More data for this Ligand-Target Pair