BDBM50088847 CHEMBL171345::N-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-benzyl}-acetamide

SMILES: CC(=O)NCc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=NPEWMGIXJNOZHY-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (BOVINE)	BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) Show SMILES CC(=O)NCc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN3O/c1-16(25)22-14-17-2-4-18(5-3-17)15-23-10-12-24(13-11-23)20-8-6-19(21)7-9-20/h2-9H,10-15H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D2				Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) Show SMILES CC(=O)NCc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN3O/c1-16(25)22-14-17-2-4-18(5-3-17)15-23-10-12-24(13-11-23)20-8-6-19(21)7-9-20/h2-9H,10-15H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99				Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human))	BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) Show SMILES CC(=O)NCc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN3O/c1-16(25)22-14-17-2-4-18(5-3-17)15-23-10-12-24(13-11-23)20-8-6-19(21)7-9-20/h2-9H,10-15H2,1H3,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99				Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) Show SMILES CC(=O)NCc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN3O/c1-16(25)22-14-17-2-4-18(5-3-17)15-23-10-12-24(13-11-23)20-8-6-19(21)7-9-20/h2-9H,10-15H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7
					More data for this Ligand-Target Pair