BDBM50088955 2-{[3-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-2-methyl-3H-benzoimidazol-5-yl]-[1-(1-imino-ethyl)-piperidin-4-yl]-amino}-acetamide::CHEMBL369480
SMILES: CC(=N)N1CCC(CC1)N(CC(N)=O)c1ccc2nc(C)n(Cc3ccc4ccc(cc4c3)C(N)=N)c2c1
InChI Key: InChIKey=QYQMIYAPIMHSEV-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50088955 (2-{[3-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-2-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Coagulation factor X | Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Bos taurus (bovine)) | BDBM50088955 (2-{[3-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-2-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description In vitro inhibitory activity against bovine cationic trypsin | Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50088955 (2-{[3-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-2-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description In vitro inhibitory activity against human coagulation factor II | Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N | |||||||||||
More data for this Ligand-Target Pair |