BDBM50089124 4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-yl]-1-methyl-piperidin-4-ol::CHEMBL284015

SMILES: CN1CCC(O)(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=ANPWOFIXNRYHFQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 (Mus musculus (mouse))	BDBM50089124 (4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-...) Show SMILES CN1CCC(O)(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H22FN3O/c1-25-12-8-21(26,9-13-25)19-14-18(15-6-10-23-11-7-15)20(24-19)16-2-4-17(22)5-3-16/h2-7,10-11,14,24,26H,8-9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of murine p38 alpha MAP kinase				Bioorg Med Chem Lett 10: 1261-4 (2000) BindingDB Entry DOI: 10.7270/Q2XS5TMT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50089124 (4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-...) Show SMILES CN1CCC(O)(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H22FN3O/c1-25-12-8-21(26,9-13-25)19-14-18(15-6-10-23-11-7-15)20(24-19)16-2-4-17(22)5-3-16/h2-7,10-11,14,24,26H,8-9,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1, COX-1				Bioorg Med Chem Lett 10: 1261-4 (2000) BindingDB Entry DOI: 10.7270/Q2XS5TMT
					More data for this Ligand-Target Pair