BDBM50089132 1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-2-yl]-cyclobutanol::CHEMBL22618

SMILES: OC1(CCC1)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=AAEBMZQCUQGRHJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 (Mus musculus (mouse))	BDBM50089132 (1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...) Show SMILES OC1(CCC1)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C18H16FN3O/c19-14-4-2-12(3-5-14)15-16(13-6-10-20-11-7-13)22-17(21-15)18(23)8-1-9-18/h2-7,10-11,23H,1,8-9H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of murine p38 alpha MAP kinase				Bioorg Med Chem Lett 10: 1261-4 (2000) BindingDB Entry DOI: 10.7270/Q2XS5TMT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50089132 (1-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-imidazol-...) Show SMILES OC1(CCC1)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C18H16FN3O/c19-14-4-2-12(3-5-14)15-16(13-6-10-20-11-7-13)22-17(21-15)18(23)8-1-9-18/h2-7,10-11,23H,1,8-9H2,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1, COX-1				Bioorg Med Chem Lett 10: 1261-4 (2000) BindingDB Entry DOI: 10.7270/Q2XS5TMT
					More data for this Ligand-Target Pair