BDBM50089146 ((3R,4S)-4-Hydroxy-1-methyl-4-phenyl-piperidin-3-yl)-phenyl-methanone::CHEMBL23638

SMILES: CN1CC[C@](O)([C@@H](C1)C(=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=TVRFABREAYQAQA-PKOBYXMFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089146 (((3R,4S)-4-Hydroxy-1-methyl-4-phenyl-piperidin-3-y...) Show SMILES CN1CC[C@](O)([C@@H](C1)C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H21NO2/c1-20-13-12-19(22,16-10-6-3-7-11-16)17(14-20)18(21)15-8-4-2-5-9-15/h2-11,17,22H,12-14H2,1H3/t17-,19+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
					More data for this Ligand-Target Pair